Would you sell your data to AI?

+ An AI medicine that fights lung disease

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Arnold Schwarzenegger wasn’t the first choice for The Terminator. O.J. Simpson was initially considered, but producers thought he was “too nice” to play a killer robot. You read that correctly.

What’s in store:

  • Website owners get to call the shots on AI crawlers.

  • AI-designed drugs are no longer a sci-fi plot—here’s proof.

  • Around the web: X's new block function allows blocked users to view posts but not interact with them.

  • Learn why we use Guidde to make all of our documentation!

Read Time: 6 minutes

AI DATA

Cloudflare has announced plans to create a marketplace next year, allowing website owners to sell access to their content to AI companies.

This is part of CEO Matthew Prince's goal to give website owners more control over how AI bots use their data. Because use it, they will.

As a first step, Cloudflare has launched a free tool called AI Audit.

This lets website owners track when and how often AI models are scraping their sites.

They can also block or allow specific AI bots with just one click, depending on their needs or deals.

The rise of AI scraping has become a concern, especially for smaller publishers whose content is used without payment.

This threatens their business models, as many depend on site traffic for revenue.

While large companies like TIME and The Atlantic have licensing deals with AI companies like OpenAI, most smaller websites do not.

Cloudflare’s marketplace hopes to change that by letting smaller publishers set their own prices for AI access to their content, whether through payment or credit.

What to know:

  • Cloudflare’s AI Audit tool allows website owners to monitor and block AI scrapers.

  • Smaller publishers will soon have a way to monetise their content through Cloudflare’s marketplace.

  • The new tools aim to give content creators more control over how AI companies use their material.

Your content, your rules

Although the details are still being worked out, Cloudflare's vision is for a system where AI companies can pay for the content they scrape.

Website owners would be able to set rates based on how often their content is accessed, either for payment or recognition.

This could change the dynamic between AI firms and content creators, giving even small sites more influence.

Cloudflare believes this approach will benefit the entire AI industry, as the current practice—where AI companies often use content without paying—is not sustainable long term.

How do you feel about AI bots finally having to pay for content scraping?

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Vote for live results and see results + opinions from yesterday at the bottom of the email.

OUR TOP TOOLS

Ever wish you could clone yourself to answer the neverending repetitive questions?

Well, with Guidde, you can!

Guidde is an AI-powered tool that can turn your instructions and explanations into neat, easy-to-follow videos in seconds.

It’s like having a digital assistant who never gets tired of explaining the same old thing for the nth time.

Whether it’s showing your team how to navigate a new software or helping customers get the most out of your product, Guidde makes it happen in record time.

Here’s how Guidde gets it done:

  • Turn boring explanations into dynamic video tutorials with just a few clicks

  • Keep your team on the same page with branded, consistent content

  • Update and edit videos with brand-new features like intros and outros

Whether you’re training new hires, or keeping your customers in the loop, Guidde does the hard work so you can focus on other things.

Trusted by 20,000+ users and rated 5 stars on the Google Chrome store, it’s the go-to tool everyone should have.

Why not give it a try? It’s free!

On This Day

September 24th 1960 - The world's first nuclear-powered aircraft carrier, the USS Enterprise, is launched at Newport News, Virginia.

Weird AI

Xiao Pang’s unexpected smash attack

A robot designed for interacting with kids ran into some unexpected trouble at the China Hi-Tech Fair. Xiao Pang, also known as “Little Fatty” or “Fabo”, was meant to display emotions and answer questions, but things took a turn when it rammed into a glass display booth, breaking the glass and injuring a man’s ankle.

The injury wasn’t too serious, he just needed a few stitches and walked away. The mishap was blamed on human error —someone hit the wrong button and sent the robot moving in the wrong direction.

AI SCIENCE

Insilico Medicine’s AI-created drug has shown promise in helping people with idiopathic pulmonary fibrosis (IPF), a lung disease that causes scarring.

In a Phase 2a trial in China, patients who took the drug had improved lung function, but there isn’t enough detail yet to compare it to other drugs in development.

The trial involved 71 patients, and the main goal was to check the safety of different doses of the drug ISM001-055.

A secondary goal was to see how it affected breathing, measured by forced vital capacity (FVC), which shows how much air a person can exhale.

Patients usually survive between three to four years after diagnosis. Current treatments slow down the disease but don’t stop it or reverse it.

Here are the findings:

  • Insilico’s drug ISM001-055 improved lung function, with the highest dose showing the most benefit.

  • IPF affects around 5 million people worldwide, with few effective treatment options.

  • Competitors like Boehringer Ingelheim and Pliant Therapeutics are also developing new drugs for IPF.

Designed by robots, tested by us

Insilico’s AI technology identified a target for the drug, the TNIK enzyme, which is linked to lung scarring.

While this enzyme has mostly been studied in cancer research, Insilico used AI to design the drug to block it, reducing scar tissue in the lungs.

Early details were published in Nature Biotechnology, showing the drug’s development and results from earlier trials.

Insilico now plans to discuss a Phase 2b trial with regulators, which will involve more patients and longer treatment periods.

Despite the positive results so far, Insilico still lags behind other drug developers like Boehringer and Pliant, who are further along with their IPF treatments.

When AI says, 'I got this,' and actually delivers. Mind blown.

Mindstream Picks

Space: NASA cancelled the VIPER lunar rover mission, fully built and tested, which we believe is a mistake, risking U.S. leadership in lunar exploration to China.

Crypto: Swiss crypto bank Sygnum announced that its Liechtenstein subsidiary has secured a crypto license under the country’s Financial Market Authority.

Games: PlatinumGames has acquired The Wonderful 101 franchise from Nintendo, though plans for sequels remain unclear.

Sports: Raheem Sterling could make his full Arsenal debut in the EFL Cup against Bolton, following Leandro Trossard’s suspension.

Don’t Miss - X has changed its blocking feature so that blocked users can still view public posts, but not interact with them. Elon Musk confirmed this, arguing that users can already see blocked content through alternative methods.

AI Art

Our Image of the Day

Artwork submitted by Mindstream reader webax: “Pirate doing yoga on a ship”

Daily Image Prompt

Alien making balloon animals

Yesterday’s Poll

“Are we about to witness the next iPhone-level moment with AI or is this just Silicon Valley doing its thing again?”

Next big thing, for sure. - 51%

Sounds cool, but I’m not sold yet. - 49%

Your Views:

“There are so much behaviours that could be better for watches or similar small devices, the intelligence of LLMs could definitely be impressive again.” - cver

“I'd want to see a bit more information first. Do we really want a device that's separate/in addition from/to our phones?” - jon.pickles

Submit your opinions in our daily poll to be featured!

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